Galgravin, CAS 528-63-2

Formulation: A solid

Formal Name: (2R,3R,4S,5S)-rel-2,5-bis(3,4-dimethoxyphenyl)tetrahydro-3,4-dimethyl-furan

Purity: ≥98%

Formula Markup: C22H28O5

Formula Weight: 372,5

Shelf life (days): 1460

CAS Number: 528-63-2

Notes: Galgravin is a lignan that has been found in N. megapotamica and has diverse biological activities.{64477,64478,64479,64480} It inhibits the binding of platelet-activating factor (PAF) to isolated rabbit platelet plasma membranes (IC50 = 4.5 µM).{64477} Galgravin (3-100 µM) inhibits osteoclast formation induced by RANKL and macrophage colony-stimulating factor (M-CSF) in mouse bone marrow-derived macrophages.{64478} It protects against cytotoxicity induced by human amyloid-β (25-35) (Aβ (25-35); Item No. 24155) in primary rat hippocampal neurons when used at a concentration of 10 µM.{64479} Galgravin (20 mg/kg) reduces acetic acid-induced abdominal constrictions in mice and carrageenan-induced paw edema in rats.{64480}

• Artikelnummer: CAY35431-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35431-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe