GAPDH antibody (HL2062)

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Clone Name: HL2062

Light Chain: Kappa

Application Note: WB: 1:1000-1:50000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 36

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Uniprot ID: P04406

Antigen Species: Human

Immunogen: Recombinant fragment of human GAPDH

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: glyceraldehyde-3-phosphate dehydrogenase

• Artikelnummer: GTX637966-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX637966-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus), Primate, Escherichia Coli, Rabbit, Cat (Feline), Dog (Canine), Hamster, Zebrafish
• Klonalität: Recombinant
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 2597
• Wirt: Rabbit
• Konjugat: Unconjugated