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CAS Number: 184475-35-2
Description: Gefitinib is a tyrosine kinase inhibitor. It is a potent inhibitor of EGFR kinase (Ki = 0.40 nM), but much weaker against ErbB-2 kinase (Ki = 870 nM) and ErbB-4 kinase (Ki = 1.1 µM).
Format: White to off-white solid.
Purity: ≥99%
Solubility: Soluble in DMSO, up to about 100 mg/ml; very poorly soluble in water or ethanol.
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Biosafety Level: Not applicable (BSL-1)
References: Wood, E.R., et al. Cancer Res. 64: 6652-6659 (2004).