GLP1R antibody (HL2298)

Clone Name: HL2298

Light Chain: Kappa

Positive Control: human pancreas,mouse pancreas,rat pancreas

Specificity/Sensitivity: This antibody was raised against human GLP1R Extracellular domain.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

Uniprot ID: P43220

Antigen Species: Human

Immunogen: Synthetic peptide encompassing a sequence within the Extracellular domain human of GLP1R. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: glucagon like peptide 1 receptor

• Artikelnummer: GTX638353-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX638353-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Human Gene ID: 2740
• Wirt: Rabbit
• Konjugat: Unconjugated