GLS2 Inhibitor Screening Assay Kit

Products from BPS Bioscience require a minimum order value above 400€

Applications: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Background: Liver-type glutaminase (GLS2) is a phosphate-activated amidohydrolase that catalyzes the hydrolysis of L-glutamine to L-glutamate and ammonia. GLS2 is related to tumor progression and cancer, including breast and hepatocellular carcinoma.

Description: The GLS2 Inhibitor Screening Assay Kit is designed to measure the hydrolase activity of GLS2 for screening and profiling applications.

Storage Stability: Up to 6 months from date of receipt, when stored as recommended.

Supplied As: The GLS2 assay kit comes in a convenient 96-well format, with purified GLS2, its substrates, the Coupling reagent, and buffer for 100 enzyme reactions.

Biosafety Level: Not applicable (BSL-1)

References: Xiang, Lisha, et al. (2013) "Knock-down of glutaminase 2 expression decreases glutathione, NADH, and sensitizes cervical cancer to ionizing radiation." Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833.12: 2996-3005.Zhang, Jianbin, et al. (2013) "Epigenetic silencing of glutaminase 2 in human liver and colon cancers." BMC cancer 13.1: 601-609.

• Artikelnummer: BPS79925
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 79925
• Green Labware: Nein
• Verpackungseinheit: 96 rxns.
• Mengeneinheit: PAK