GLS4, CAS 1092970-12-1

Formulation: A solid

Formal Name: 4-(2-bromo-4-fluorophenyl)-1,4-dihydro-6-(4-morpholinylmethyl)-2-(2-thiazolyl)-5-pyrimidinecarboxylic acid, ethyl ester

Purity: ≥98%

Formula Markup: C21H22BrFN4O3S

Formula Weight: 509,4

Shelf life (days): 1460

CAS Number: 1092970-12-1

Notes: GLS4 is an antiviral agent.{67098} It inhibits the replication of wild-type hepatitis B virus (HBV) and the drug-resistant HBV strains rtA181T, rtA181V, and rtN236T (IC50s = 146, 145, 161, and 131 nM, respectively). GSL4 (1 and 10 µM) inhibits the formation of viral capsids and decreases viral core protein levels in HBV-infected HepG2 and HepG2.2.15 cells. It inhibits HBV replication and reduces the levels of viral intracellular core antigens in mice inoculated with HepAD38 cells, which carry and replicate HBV, when administered at doses ranging from 7.5 to 60 mg/kg.{67099}

• Artikelnummer: CAY35843-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35843-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK
• Methode: Reinstoffe