GPS2 antibody (HL2276)

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Clone Name: HL2276

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 37

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]

Uniprot ID: Q13227

Antigen Species: Human

Immunogen: Recombinant fragmemt of human GPS2.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: G protein pathway suppressor 2

• Artikelnummer: GTX638329-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX638329-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus), Zebrafish
• Klonalität: Recombinant
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 2874
• Wirt: Rabbit
• Konjugat: Unconjugated