Griselimycin, CAS 26034-16-2

Formulation: A solid

Formal Name: N-acetyl-N-methyl-L-valyl-(4R)-4-methyl-L-prolyl-N-methyl-L-threonyl-L-leucyl-(4R)-4-methyl-L-prolyl-L-leucyl-N-methyl-L-valyl-L-prolyl-N-methyl-D-leucyl-glycine, (10→3)-lactone

Purity: ≥98%

Formula Markup: C57H96N10O12

Formula Weight: 1113,4

Shelf life (days): 1095

CAS Number: 26034-16-2

Notes: Griselimycin is a cyclic depsipeptide that has been found in Streptomyces and has antibacterial activity.{65814,65815} It is active against M. tuberculosis strain H37Rv (MICs = 1-1.2 and 6.2 µg/ml in liquid culture and RAW 264.7 macrophages, respectively) but associated with resistance.{65815} Griselimycin inhibits the protein-protein interaction between the M. smegmatis DNA polymerase sliding clamp, DnaN, and M. smegmatis DNA polymerase, leading to inhibition of DNA replication.

• Artikelnummer: CAY39306-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39306-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK