GRM1 Polyclonal Antibody, Rabbit

GRM1 Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-92502-120
Verpackungseinheit
120 µl
Hersteller
Elabscience Biotechnology

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Abbreviation: GRM1

Target Synonym: GRM1;GPRC1A;MGLU1;MGLUR1;PPP1R85;SCAR13

Conjugation: Unconjugated

UNIProt ID: Q13255

Background: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human GRM1

Dilution: WB 1:500-1:2000
Mehr Informationen
Artikelnummer ELSE-AB-92502-120
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer ELA-E-AB-92502-120
Green Labware Nein
Verpackungseinheit 120 µl
Mengeneinheit STK
Reaktivität Mouse (Murine)
Klonalität Polyclonal
Methode Western Blotting
Isotyp IgG
Wirt Rabbit
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