GSK3α Assay Kit

Products from BPS Bioscience require a minimum order value above 400€

Applications: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Background: GSK3 (Glycogen synthase kinase) is a serine/threonine kinase which initially was found to phosphorylate and inactivate glycogen synthase in glycogen biosynthesis. It is an important regulator enzyme in many disease pathogeneses including cancer, immune disorders, metabolic disorders and neurological disorders like Alzheimer's disease. Recently, GSK3α, one of the isoforms of GSK3, was identified as a key target in acute myeloid leukemia (AML).

Contraindications: Keep final DMSO concentration below 1%

Description: The GSK3α Assay Kit is designed to measure GSK3α activity for screening and profiling applications using Kinase-Glo® (Promega) as a detection reagent.

Storage Stability: Up to 6 months when stored as recommended.

Warnings: Avoid multiple freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: McCubrey JA., et al. Oncotarget 5(10): 2881-2911 (2014)

• Artikelnummer: BPS79698
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 79698
• Green Labware: Nein
• Verpackungseinheit: 96 rxns.
• Mengeneinheit: PAK