GW 441756, CAS 504433-23-2

NGFR kinase inhibitor

Product Type: Inhibitor

CAS No.: 504433-23-2

MolecularFormula: C17H13N3O

Molecular Weight: 275,3

Source: Synthetic

Purity: >99 %

Solubility: Soluble to 15 mM in DMSO

Appearance: Red solid

PubChem CID: 9943465

Scientific Background: GW 441756 is a potent and selective NGF receptor tyrosine kinase A (TrkA) inhibitor. Specifically, it is shown to block apoptosis and cell death induced by TrkA. GW-441756 displays > 100-fold selectivity over a range of other kinases.

References: 1. Wood E.R., et al. (2004) Bioorganic & Med. Chem. Ltr. 14(4): 953–957.2. Jung E.J., Kim C.W., & Kim D.R. (2008) Exp. Mol. Med. 40(3): 276–285.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-450-10MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-450-10MG
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK