H2AFX Antibody - N-terminal region : FITC

H2AFX Antibody - N-terminal region : FITC
Artikelnummer
AVIARP58280_P050FITC
Verpackungseinheit
100μl
Hersteller
Aviva Systems Biology

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Conjugation: FITC: Fluorescein Isothiocyanate

Description of Target: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H2AFX is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human H2AFX

Key Reference: Scherthan,H., (2008) Biochem. Biophys. Res. Commun. 371 (4), 694-697

Molecular Weight: 16kDa

Peptide Sequence: Synthetic peptide located within the following region: SGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVY

Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.

Protein Name: Histone H2A.x

Protein Size: 143

Purification: Affinity Purified
Mehr Informationen
Artikelnummer AVIARP58280_P050FITC
Hersteller Aviva Systems Biology
Hersteller Artikelnummer ARP58280_P050-FITC
Green Labware Nein
Verpackungseinheit 100μl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Guinea Pig, Cow (Bovine), Zebrafish, Horse (Equine)
Klonalität Polyclonal
Methode Western Blotting
Human Gene ID 3014
Wirt Rabbit
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