Product Description: HE-S2 is an antibody-drug conjugate triggering a potent antitumor immune response. HE-S2 acts by blocking the PD-1/PD-L1 interaction and activating the Toll-like receptor 7/8 (TLR7/8) signaling pathway. HE-S2 has remarkable antitumor activity[1].
Applications: COVID-19-immunoregulation
Formula: C38H45N9O6S2
References: [1]He L, et al. Immune Modulating Antibody-Drug Conjugate (IM-ADC) for Cancer Immunotherapy. J Med Chem. 2021;64(21):15716-15726.
CAS Number: 2939851-67-7
Molecular Weight: 787.95
Research Area: Cancer; Infection
Solubility: 10 mM in DMSO
Target: Drug-Linker Conjugates for ADC;PD-1/PD-L1;Toll-like Receptor (TLR)