Target Synonym: H1.6;H1FT;H1t;dJ221C16.2;HIST1H1T
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Immunogen: A synthetic peptide of human Histone H1t
Dilution: WB 1:500-1:2000;IHC 1:50-1:200
Calculated MW: 22kDa
Observed MW: 30kDa
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