Histone H2b, Full Length, His-tag Recombinant

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Encompassing Amino Acids: 2-126(end)

Applications: Useful as a substrate for histone methyltransferase and acetyltransferase assays. Ideal for screening small molecular inhibitors of histone modifying enzymes for drug discovery and HTS applications.

Description: Human Histone 2B, GenBank Accession No. NM_003528, a.a. 2-126(end) with N-terminal His-tag, MW = 14.6 kDa, expressed in an E. coli expression system.

Format: Aqueous buffer solution

Formulation: 50 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol, 1 mM PMSF and 1 mM DTT.

Genbank: NM_003528

Host Cell Line: E. coli

Storage Stability: At least 6 months at -80°C.

Tags: N-terminal His-tag

Uniprot: Q16778

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Osley, M.A., Brief Funct. Genomic. Proteomic. 5(3):179-89 (2006).
2. Wyrick, J.J. and Parra, M.A., Biochim. Biophys Acta. 1789(1):37-44 (2009).
3. Emre, N.C. and Berger, S.L., Cold Spring Harb Symp Quant Biol. 69:289-99 (2004)Application Reference(s):
Differential mode of antimicrobial actions of arginine-rich and lysine-rich histones against Gram-positive Staphylococcus aureus (2013)

• Artikelnummer: BPS52022
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 52022
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK