HLA-DRB (MHC II)(Bra30), 1mg/mL

Description: This MAb reacts with the HLA-DRB3 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: Bra30

Entrez Gene ID: 3123

Immunogen: Human REH cells (non-T, non-B leukemia cell line)

Expected AB Applications: Flow, surface (published for clone)/Functional studies (published for clone)/WB (published for clone)

Z-Antibody Applications: Flow, surface (published)/Functional studies (published)/WB (published)

• Artikelnummer: BTMBNUM0407-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM0407-50
• Green Labware: Nein
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human, Primate, Monkey (Primate), Dog (Canine), Various species
• Klonalität: Monoclonal
• Methode: Western Blotting, Flow Cytometry, Functional Studies
• Isotyp: IgG2a kappa
• Wirt: Mouse