HSP90α (C-Terminal Domain) TR-FRET Kit

Products from BPS Bioscience require a minimum order value above 400€

Applications: Great for screening small molecular inhibitors for drug discovery and HTS applications.

Description: The HSP90α (C-Terminal Domain) TR-FRET assay kit is designed to measure the inhibition ofHSP90α binding to its protein target PPID (also known as Cyclophilin D or Cyp40) in ahomogeneous, 384 reaction format. This assay requires no time-consuming washing steps,making it especially suitable for high throughput screening applications. The assay procedure isstraightforward and simple. A sample containing terbium-labeled donor, dye-labeled acceptor,HSP90α, substrate, and an inhibitor is incubated for 2 hours. The protein-protein interaction isthen assayed by measuring the TR-FRET between the PPID and HSP90α using a fluorescencereader.

Storage Stability: Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.

Supplied As: Kit comes in a homogeneous, 384 reaction format

Uniprot: P07900

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: Allan, R.K. et al. J. Biol. Chem. 2006 281(11): 7161-71

• Artikelnummer: BPS50261
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 50261
• Green Labware: Nein
• Verpackungseinheit: 384 rxns.
• Mengeneinheit: PAK