Human FGFR2 alpha IIIc (extracellular region) protein, His tag

Species: Human

Form: Liquid

Buffer (with preservative): PBS, 20% Glycerol, no preservative.

Concentration: batch dependent (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]

Uniprot ID: P21802

Region Sequence: C-terminal 10 x His tagged ; 22-377 aa (Uniprot #P21802-1)

ExpressionSystem: HEK293 cells

Conjugation: Unconjugated

Full Name: fibroblast growth factor receptor 2

• Artikelnummer: GTX02784-PRO-50
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02784-PRO-50
• Green Labware: Nein
• Verpackungseinheit: 50 μg
• Mengeneinheit: STK
• Human Gene ID: 2263