Human IL4 protein, His tag (active)

Species: Human

Application Note: Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED₅₀ range ≤ 0.5 ng/ml.

Calculated MW: 17

Form: Liquid

Buffer (with preservative): PBS, 10% Glycerol, no preservative.

Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Background: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Uniprot ID: P05112

Region Sequence: His-Tagged, 25-153aa (P05112, NP_000580)

ExpressionSystem: HEK293 cells

Conjugation: Unconjugated

Full Name: interleukin 4

• Artikelnummer: GTX02862-pro-50
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02862-pro-50
• Green Labware: Nein
• Verpackungseinheit: 50 μg
• Mengeneinheit: STK
• Methode: Functional Assay
• Human Gene ID: 3565