hVEGF-IN-1, CAS 1637443-98-1

Formulation: A solid

Formal Name: N-[2-[4-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-2-quinazolinyl]phenyl]-4-methyl-1-piperazinepropanamide

Purity: ≥98%

Formula Markup: C34H43N7O2

Formula Weight: 581,8

Shelf life (days): 1460

CAS Number: 1637443-98-1

Notes: hVEGF-IN-1 is an inhibitor of VEGFA translation.{67375} It binds to the mRNA encoding VEGF-A (Kd = 4.64 µM) and decreases its translation when used at a concentration of 1.5 µM. hVEGF-IN-1 (3 µM) reduces migration of MCF-7 breast cancer cells. It decreases tumor growth and weight without reducing body weight in an MCF-7 mouse xenograft model when administered at a dose of 7.5 mg/kg per day.

• Artikelnummer: CAY37550-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37550-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe