ICOS (CD278), Fc fusion (Human) Recombinant

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Encompassing Amino Acids: 21-140

Applications: Useful for studying protein binding and for screening small molecules and antibodies.

Description: Human ICOS, Fc fusion protein, also known as inducible T-cell costimulator and CD antigen 278, activation-inducible lymphocyte immunomediatory molecule, AILIM, CD278, and CVID1. GenBank Accession No. NM_012092, a.a. 21-140 expressed in a HEK293 cell expression system. MW = 40.2 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Endotoxin Level: <1 EU/µg

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Genbank: NM_012092

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal Fc fusion (Human IgG1)

Uniprot: Q9Y6W8

Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.

Biosafety Level: Not applicable (BSL-1)

References: 1. Hutloff, A. et al., Nature. 1999; 397: 263- 266.
2. Dong, C. et al., Nature. 2001; 409: 97- 101.

• Artikelnummer: BPS71179
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71179
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK