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Product Description: IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (His) is the recombinant human-derived IGF-I R protein, expressed by E. coli , with N-6*His labeled tag. The total length of IGF-I R Protein, Human (His) is 169 a.a., with molecular weight of ~27 kDa.Artikelnummer | MEXHY-P72256-100UG |
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Hersteller | MedChemExpress |
Hersteller Artikelnummer | HY-P72256-100UG |
Verpackungseinheit | 100 μg |
Mengeneinheit | STK |
Produktinformation (PDF) |
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MSDS (PDF) |
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