IGF1R beta antibody (HL1958)

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Clone Name: HL1958

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 155

Specificity/Sensitivity: This antibody was raised against human IGF1R beta Extracellular domain.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Uniprot ID: P08069

Antigen Species: Human

Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human IGF1R beta. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: insulin like growth factor 1 receptor

• Artikelnummer: GTX637795-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX637795-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Recombinant
• Methode: Immunohistochemistry (paraffin), Western Blotting
• Isotyp: IgG
• Human Gene ID: 3480
• Wirt: Rabbit
• Konjugat: Unconjugated