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IL-2 Luciferase Reporter Jurkat Cell Line
IL-2 Luciferase Reporter Jurkat Cell Line
Artikelnummer
BPS60481
Verpackungseinheit
2 vials
Hersteller
BPS Bioscience
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Applications: The IL-2-luciferase Jurkat reporter cell line is suitable for monitoring the transcription activity of IL-2 in response to stimulants, and establishing cell-based screens for inhibitors that target specific IL-2 stimulating molecules.
Background: Interleukin-2 (IL-2) is a key cytokine important for proliferation and differentiation of T cells into effector T cells through interaction with the IL-2 receptor.
Description: Human IL-2 reporter construct is stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by a human IL-2 promoter.
Format: Each vial contains ~2 x 10^6 cells in 1 ml of 10% DMSO in FBS.
Host Cell Line: Jurkat
Mycoplasma Testing: This cell line has been screened using the MycoAlert™ Mycoplasma Detection Kit (Cat. No. LT07-118) to confirm the absence of Mycoplasma contamination. MycoAlert Assay Control Set (Cat. No. LT07-518) was used as a positive control.
Storage Stability: Store in liquid nitrogen immediately upon receipt.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: BSL-1
References: 1.Weaver JR et.al. (2007) Characterization of the sequence and architectural constraints of the regulatory and core regions of the human interleukin-2 promoter. Mol. Immunol. 44: 2813-2819.2.Hughes CCW and Pober JS (1996) Transcriptional Regulation of the Interleukin-2 Gene in Normal Human Peripheral Blood T Cells. J. Biol. Chem. 271: 5369-5377.
Applications: The IL-2-luciferase Jurkat reporter cell line is suitable for monitoring the transcription activity of IL-2 in response to stimulants, and establishing cell-based screens for inhibitors that target specific IL-2 stimulating molecules.
Background: Interleukin-2 (IL-2) is a key cytokine important for proliferation and differentiation of T cells into effector T cells through interaction with the IL-2 receptor.
Description: Human IL-2 reporter construct is stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by a human IL-2 promoter.
Format: Each vial contains ~2 x 10^6 cells in 1 ml of 10% DMSO in FBS.
Host Cell Line: Jurkat
Mycoplasma Testing: This cell line has been screened using the MycoAlert™ Mycoplasma Detection Kit (Cat. No. LT07-118) to confirm the absence of Mycoplasma contamination. MycoAlert Assay Control Set (Cat. No. LT07-518) was used as a positive control.
Storage Stability: Store in liquid nitrogen immediately upon receipt.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: BSL-1
References: 1.Weaver JR et.al. (2007) Characterization of the sequence and architectural constraints of the regulatory and core regions of the human interleukin-2 promoter. Mol. Immunol. 44: 2813-2819.2.Hughes CCW and Pober JS (1996) Transcriptional Regulation of the Interleukin-2 Gene in Normal Human Peripheral Blood T Cells. J. Biol. Chem. 271: 5369-5377.
| Artikelnummer | BPS60481 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 60481 |
| Verpackungseinheit | 2 vials |
| Mengeneinheit | PAK |
| Wirt | Human |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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