IL-27/p28 Mouse Recombinant Protein

Application Note: IL-27/p28 protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-IL-27/p28 in immunological assays. Buffer Formulation: 10 mM sodium bicarbonate, pH 8.5.

Concentration Value: 0.1 mg/mL

General Disclaimer Note: This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Other Performance Data: Biological Activity: Mouse p28 biological activity was measured via dose-dependent inhibition of TGFß and IL-6-induced IL-17A expression in mouse CD4 splenocytes. 50ng/ml of Mouse p28 is capable of inhibiting >25% of IL-17A expression in this assay. no acceptance criteria limits established. Endotoxin Level: Measured by LAL is typically ≤ 1 EU/μg (with a 50% confidence range).

Physical State: Lyophilized

Purity and Specificity: Purity was determined to be approximately 97% as determined by reducing and non-reducing SDS-PAGE.

Background: Mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions. Recombinant mouse p28 is a single-chain 207 amino acid peptide with a mass of approximately 23,697 Daltons.

Low Endotoxin: Yes

Other: User Optimized

• Artikelnummer: ROC010-001-B54
• Hersteller: Rockland
• Hersteller Artikelnummer: 010-001-B54
• Verpackungseinheit: 10 µg
• Mengeneinheit: STK
• Methode: SDS-PAGE
• Konjugat: Unconjugated