IL1 beta antibody (7P10) (Biotin)

Clone Name: 7P10

Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 31

Specificity/Sensitivity: This antibody is able to detect native and recombinant human IL-1β, binds to the pro-form and active form of IL-1β, and has no cross-reactivity with IL-1α.

Form: Liquid

Buffer (with preservative): PBS, 0.02% Sodium azide.

Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Uniprot ID: P01584

Antigen Species: Human

Immunogen: Recombinant human IL-1β

Purification: Protein G purified

Conjugation: Biotin

Full Name: interleukin 1 beta

• Artikelnummer: GTX02971-02-250
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02971-02-250
• Green Labware: Nein
• Verpackungseinheit: 250 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: ELISA
• Isotyp: IgG2b
• Human Gene ID: 3553
• Wirt: Mouse