IL10 antibody (9D7)

Clone Name: 9D7

Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 21

Specificity/Sensitivity: This antibody is able to detect native and recombinant human IL-10.

Form: Liquid

Buffer (with preservative): PBS, 0.02% Sodium azide.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]

Uniprot ID: P22301

Antigen Species: Human

Immunogen: Recombinant human IL-10

Purification: Protein G purified

Conjugation: Unconjugated

Full Name: interleukin 10

• Artikelnummer: GTX02950-250
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02950-250
• Green Labware: Nein
• Verpackungseinheit: 250 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: ELISA
• Isotyp: IgG1
• Human Gene ID: 3586
• Wirt: Rat