IL18 Polyclonal Antibody, Rabbit

Abbreviation: IL18

Target Synonym: Ig; Il-; Igif; Il-18

Conjugation: Unconjugated

UNIProt ID: P70380

Background: Interleukin-18 (L-18) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of mouse IL18

Dilution: WB 1:500-1:2000,IHC 1:50-1:200

• Artikelnummer: ELSE-AB-93262-120
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-93262-120
• Green Labware: Nein
• Verpackungseinheit: 120 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Western Blotting, Immunohistochemistry
• Isotyp: IgG
• Wirt: Rabbit