iLite® ADCP Effector, Assay Ready Cells

iLite® ADCP Effector Assay Ready Cells are human engineered cells (Jurkat, ATCC #TIB-152) optimized to express high levels of the low affinity Fc receptor FcγRIIa (CD32), and the Firefly Luciferase (FL) reporter gene regulated by the NFAT response element. The ADCP reporter bioassay can be used to screen for biologics and other drugs via binding and activation of the FcγRIIa receptor.

Normalization of cell counts, serum matrix effects or lysis of the effector cells by the target cells is obtained by a second reporter gene, a Renilla Luciferase reporter gene construct, under control of a constitutive promotor.

• Artikelnummer: WIEBM5004
• Hersteller: Svar Life Science / Eurodiagnostica
• Hersteller Artikelnummer: BM5004
• Verpackungseinheit: 250 µL
• Mengeneinheit: PAK