Conjugation: HRP: Horseradish Peroxidase
Description of Target: IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. IMPA1 can use myo-inositol monophosphates, myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IMPA1
Key Reference: Ohnishi,T., (2007) J. Biol. Chem. 282 (1), 637-646
Molecular Weight: 30kDa
Peptide Sequence: Synthetic peptide located within the following region:
IVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDEProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Inositol monophosphatase 1
Protein Size: 277
Purification: Affinity Purified