Product Type: Inhibitor
CAS No.: 160807-49-8
MolecularFormula: C16H11N3O2
Molecular Weight: 277,3
Source: Synthetic
Purity: ≥98% (HPLC)
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Appearance: Red solid
PubChem CID: 5326739
Scientific Background: Indirubin-3'-monoxime is an inhibitor of protein kinases and cyclin-dependent kinases. Specifically, it is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β).
References: 1. Damiens E., Baratte B., Marie D., Eisenbrand G., & Meijer L. (2001) Oncogene. 20(29): 3786–3797.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.