Nachdem die neu aufgekommene Omikron-Variante immer mehr an Bedeutung gewinnt, rückt auch die Forschung die neue Variante B.1.1.529 immer mehr in den Vordergrund. Um das zu ermöglichen arbeitet unser Lieferant eENZYME auf Hochtouren daran neue Spike RBD Proteine und pseudovirale Partikel zur Omikron-Variante zu produzieren.

Voraussichtlich ab 21.12.2021 bei uns erhältlich:


Recombinant Protein & Pseudovirus von eENZYME:

SCV2-RBD-Omicron

Name

Spike RBD protein (SARS-CoV-2 Omicron variant, B.1.1.529)

Description

C-terminal His-tagged recombinant spike RBD protein (SARS-CoV-2 Omicron variant, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H)

Source

Glycosylated recombinant viral protein expressed and purified from HEK293 cells

Application

Western blot standard, antibody ELISA, immunogen, etc.

Purity

> 90% (SDS-PAGE)

Size

50 µg

 

SCV2-PsV-Omicron

Name

SARS-CoV-2 Pseudoviral Particles, Omicron Variant (B.1.1.529)

Description

The SARS-CoV-2 Pseudoviral Particles are replication-deficient Maloneymurine leukemia virus (MLV or MuLV) pseudotyped with the SARS-CoV-2 spike protein carrying the Omircon variant genotype.
MLV-based virus system is a better choice than HIV-based lentivirus system for making pseudoviral particles in regards of lab safety and product quality. Gag-Pol is the only component from MLV.

Applications

Our Pseudovirus Particles generate robust chemiluminescent signals in cell assays when coupled with our firefly luciferase assay kit (Catalog # CA-L165), useful for 1) screening potential inhibitors to block SARS-CoV-2 entry and viral protein; 2) measuring the activity of and screening for neutralizing antibody against SARS-CoV-2. 

Size

10 ml (2 tubes, 5 mL/tube), for 2 multi-well plates. 

Storage

 -70oC. Shipped on dry ice.

Note

1. Amenable to HTS format (96-well, 384-well and 1536-well format). 
2. HEK293-hACE2 stable cells are available seperately (Cat..#  CL-hACE2-001, CL-hACE2-002)