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Insulin antibody (HL1393)
Insulin antibody (HL1393)
Artikelnummer
GTX636833-100
Verpackungseinheit
100 μl
Hersteller
GeneTex
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Clone Name: HL1393
Light Chain: Kappa
Application Note: IHC-P: 1:100-1:5000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 12
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Uniprot ID: P01308
Antigen Species: Human
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human insulin. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: insulin
Light Chain: Kappa
Application Note: IHC-P: 1:100-1:5000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 12
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Uniprot ID: P01308
Antigen Species: Human
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human insulin. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: insulin
| Artikelnummer | GTX636833-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX636833-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 μl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus) |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (paraffin), Western Blotting |
| Isotyp | IgG |
| Human Gene ID | 3630 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
