Clone Name: HMa2
Product Description: The HMa2 antibody reacts with mouse CD49b, a 150 kDa glycoprotein member of the integrin αfamily. CD49b, also known as integrin αalpha2, associates non-covalently with CD29 (integrin αbeta1) to form the VLA-2 heterodimer. VLA-2 integrin αs function as cellular receptors for collagen and laminin. CD49b is expressed by platelets, intestinal epithelial cells, NK cells, epithelial cells, and a subset of CD4+ T cells. CD49b plays an essential role in mediating the adhesion of cells to the extracellular matrix.
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 129
Form: Liquid
Buffer (with preservative): 10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Uniprot ID: Q62469
Purification: Purified by affinity chromatography
Conjugation: Biotin
Full Name: integrin alpha 2