IRF9 Polyclonal Antibody, Rabbit

Abbreviation: IRF9

Target Synonym: IRF9; IRF-9; ISGF3; ISGF3G; p48; interferon regulatory factor 9

Conjugation: Unconjugated

UNIProt ID: Q00978

Background: Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta. Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1 are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human IRF9

Dilution: WB 1:500-1:2000

• Artikelnummer: ELSE-AB-92343-60
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-92343-60
• Green Labware: Nein
• Verpackungseinheit: 60 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit