ITPR2 Polyclonal Antibody, Rabbit

Abbreviation: ITPR2

Target Synonym: ANHD;CFAP48;INSP3R2;IP3R2;ITPR2

Conjugation: Unconjugated

UNIProt ID: Q14571

Background: The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production. [provided by RefSeq, Apr 2015]

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human ITPR2

Dilution: IHC 1:50-1:200

• Artikelnummer: ELSE-AB-92150-60
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-92150-60
• Green Labware: Nein
• Verpackungseinheit: 60 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunohistochemistry
• Isotyp: IgG
• Wirt: Rabbit