Product Type: Inhibitor
CAS No.: 314245-33-5
MolecularFormula: C18H21FN2O
Molecular Weight: 300,4
Source: Synthetic
Purity: >98%
Solubility: Soluble in 30 mg/ml DMSO, 15 mg/ml Ethanol
Appearance: Beige Solid
PubChem CID: 675434
Scientific Background: Selective inhibitor of Usp14 (IC50<4 M). Enhances proteasome activity and substrate proteolysis. Cell permeable.
References: 1. Lee B.H., et al. (2010) Nature 467: 1179.2. Lee B.H., et al. (2010) Mol. Cell. Proteomics 10: R1100003871.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.