Kallikrein 7 antibody (MSVA-707M) HistoMAX™

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Clone Name: MSVA-707M

Light Chain: Kappa

Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.

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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 28

Positive Control: Skin: A strong KLK7 staining should be seen in the stratum granulosum and possibly also in the keratinizing cell layers.

Negative Control: Colon: KLK7 immunostaining should be absent in all cells of the colon mucosa

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]

Uniprot ID: P49862

Antigen Species: Human

Immunogen: Recombinant human KLK7 protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: kallikrein related peptidase 7

• Artikelnummer: GTX04475-S-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04475-S-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2b
• Human Gene ID: 5650
• Wirt: Mouse
• Konjugat: Unconjugated