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Kallikrein 7 antibody (MSVA-707M) HistoMAX™
Kallikrein 7 antibody (MSVA-707M) HistoMAX™
Artikelnummer
GTX04475-500
Verpackungseinheit
500 μl
Hersteller
GeneTex
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Clone Name: MSVA-707M
Light Chain: Kappa
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 28
Positive Control: Skin: A strong KLK7 staining should be seen in the stratum granulosum and possibly also in the keratinizing cell layers.
Negative Control: Colon: KLK7 immunostaining should be absent in all cells of the colon mucosa
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
Uniprot ID: P49862
Antigen Species: Human
Immunogen: Recombinant human KLK7 protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: kallikrein related peptidase 7
Light Chain: Kappa
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 28
Positive Control: Skin: A strong KLK7 staining should be seen in the stratum granulosum and possibly also in the keratinizing cell layers.
Negative Control: Colon: KLK7 immunostaining should be absent in all cells of the colon mucosa
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
Uniprot ID: P49862
Antigen Species: Human
Immunogen: Recombinant human KLK7 protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: kallikrein related peptidase 7
| Artikelnummer | GTX04475-500 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX04475-500 |
| Green Labware | Nein |
| Verpackungseinheit | 500 μl |
| Mengeneinheit | STK |
| Reaktivität | Human |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (paraffin) |
| Isotyp | IgG2b |
| Human Gene ID | 5650 |
| Wirt | Mouse |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
