Product Description: KB-5492 anhydrous is a potent and selective inhibitor of sigma receptor, inhibits specific [3H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC50 of 3.15 μM. KB-5492 anhydrous is an anti-ulcer agent[1][2].
Applications: COVID-19-immunoregulation
Formula: C27H34N2O10
References: [1]Harada Y, et, al. Receptor binding profiles of KB-5492, a novel anti-ulcer agent, at sigma receptors in guinea-pig brain. Eur J Pharmacol. 1994 May 2; 256(3): 321-8./[2]Morimoto Y, et, al. Effects of KB-5492, a new anti-ulcer agent, on ethanol- and acidified aspirin-induced gastric mucosal damage in vivo and in vitro. Jpn J Pharmacol. 1994 Jan; 64(1): 41-7.
CAS Number: 129200-10-8
Molecular Weight: 546.57
Compound Purity: 99.50
Research Area: Inflammation/Immunology
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: Sigma Receptor
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