KB-R7943 mesylate, CAS 182004-65-5

TRPC channel blocker

Product Type: Inhibitor

CAS No.: 182004-65-5

MolecularFormula: C16H17N3O3S•CH3SO3H

Molecular Weight: 427,29

Source: Synthetic

Purity: >98% (TLC); NMR (Conforms)

Solubility: Soluble to 100 mM in DMSO

Appearance: White Solid

PubChem CID: 9823846

Scientific Background: KN-R9743 mesylate is a potent selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger. It also inhibits the mitochondrial Ca2+ uniporter. It does not affect Na+ dependent transport systems or ionotropic glutamate receptors.

References: 1. Hoyt K.R., Arden S.R., Aizenman E. and Reynolds I.J. (1998) Mol Pharmacol. 53(4): 742-749.2. Schroder U.H., Breder J, Sabelhaus C.F., Reymann K.G. (1999) Neuropharm. 38(2): 319-321.3. Watano T., Harada Y., Harada K., Nishimura N. (1999) Br J Pharmacol. 127(8): 1846-1850.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-312-10MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-312-10MG
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK