English
KDM2A Polyclonal Antibody, Rabbit
KDM2A Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-92104-60
Verpackungseinheit
60 µl
Hersteller
Elabscience Biotechnology
Verfügbarkeit:
wird geladen...
Preis wird geladen...
Abbreviation: KDM2A
Target Synonym: KDM2A; CXXC8; FBL11; FBL7; FBXL11; JHDM1A; LILINA; lysine demethylase 2A
Conjugation: Unconjugated
UNIProt ID: Q9Y2K7
Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human KDM2A
Dilution: WB 1:500-1:2000
Target Synonym: KDM2A; CXXC8; FBL11; FBL7; FBXL11; JHDM1A; LILINA; lysine demethylase 2A
Conjugation: Unconjugated
UNIProt ID: Q9Y2K7
Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human KDM2A
Dilution: WB 1:500-1:2000
| Artikelnummer | ELSE-AB-92104-60 |
|---|---|
| Hersteller | Elabscience Biotechnology |
| Hersteller Artikelnummer | ELA-E-AB-92104-60 |
| Green Labware | Nein |
| Verpackungseinheit | 60 µl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine) |
| Klonalität | Polyclonal |
| Methode | Western Blotting |
| Isotyp | IgG |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
Verwandte Artikel
Markieren Sie die Artikel, um Sie dem Warenkorb hinzuzufügen oder
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
