Target Synonym: HIST4H4; H4/p; histone H4
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Immunogen: A synthetic acetylated peptide around K12 of human Histone H4
Dilution: WB 1:500-1:2000
Calculated MW: 11kDa
Observed MW: 11KDa
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