Target Synonym: TDP2; AD022; EAP2; EAPII; TTRAP; dJ30M3.3; hTDP2; tyrosyl-DNA phosphodiesterase 2
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Immunogen: Recombinant fusion protein of human TDP2
Dilution: WB 1:500-1:2000
Calculated MW: 32kDa/40kDa/44kDa
Observed MW: 41KDa