Ku80 antibody (MSVA-880M) HistoMAX™

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Clone Name: MSVA-880M

Light Chain: Kappa

Product Description: This antibody was validated on 76 different Normal and cancerTissues by IHC-P.

Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 83

Positive Control: Tonsil: A strong staining should be seen in the nuclei of all cells.

Negative Control: A tumor or a cell line with documented loss of Ku80 expression.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Uniprot ID: P13010

Antigen Species: Human

Immunogen: Recombinant human XRCC5 fragmen

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: X-ray repair cross complementing 5

• Artikelnummer: GTX04480-500
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04480-500
• Verpackungseinheit: 500 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG1/IgG2b
• Human Gene ID: 7520
• Wirt: Mouse
• Konjugat: Unconjugated