LAU-0901, CAS 727358-25-0

Formulation: A solid

Formal Name: 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylic acid, 3-[2-(3,4-dichlorophenoxy)ethyl] 5-[2-(4-morpholinyl)-1-(4-morpholinylmethyl)ethyl] ester

Purity: ≥95%

Formula Markup: C29H39Cl2N3O7

Formula Weight: 612,5

Shelf life (days): 1460

CAS Number: 727358-25-0

Notes: LAU-0901 is a platelet-activating factor (PAF) receptor antagonist.{51330},{51331} In vivo, LAU-0901 (30, 60, and 90 mg/kg) reduces infarct volume and improves neurological function in a rat model of cerebral ischemia induced by middle cerebral artery occlusion (MCAO).{51330} It also reduces microglial infiltration and increases astrocytic and neuronal survival in the same model.{51331} LAU-0901 (30 mg/kg) alone, or in combination with atorvastatin (Item No. 10453), reduces tumor growth in a U87MG glioblastoma mouse orthotopic tumor model.{51332}

• Artikelnummer: CAY38414-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38414-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe