Lentztrehalose A, CAS 1609356-99-1

Formulation: A solid

Formal Name: α-D-glucopyranosyl 4-O-[(2S)-2,3-dihydroxy-3-methylbutyl]-α-D-glucopyranoside

Purity: ≥80%

Formula Markup: C17H32O13

Formula Weight: 444,4

Shelf life (days): 1460

CAS Number: 1609356-99-1

Notes: Lentztrehalose A is a disaccharide microbial metabolite that has been found in Lentzea and has diverse biological activities.{66363,66364,66365} It selectively inhibits M. smegmatis trehalase, a trehalose metabolizing enzyme, over porcine kidney trehalase (IC50s = 0.67 and >20 mM, respectively).{66364} Lentztrehalose A (100 mM) induces autophagy in MeWo melanoma and OVK18 ovarian cancer cells.{66365} It increases survival percentage and decreases tumor proliferation in a Sarcoma 180 murine sarcoma model when administered at a dose of 50 mg/kg per day.{66363}

• Artikelnummer: CAY37732-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37732-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe