Product Type: Inhibitor
CAS No.: 111358-88-4
MolecularFormula: C26H21N3O4
Molecular Weight: 439,5
Source: Synthetic
Purity: ≥98% (HPLC)
Solubility: Soluble to 100 mM in DMSO and to 25 mM in ethanol
Appearance: White powder
PubChem CID: 126565
Scientific Background: Lestaurtinib is potent JAK2, FLT3 and TrkA receptor tyrosine kinase inhibitor. Specifically, it prevents STAT5 phosphorylation. Lestaurtinib exhibits antiproliferative activity in vitro.
References: 1. Weisel K.C., et al. (2007) Ann. NY Acad. Sci. 1106: 190–196.2. Hexner E.O., et al. (2008) Blood. 111(12): 5663–5671.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.