Lintuzumab, CAS 166089-32-3

Description: Lintuzumab (HuM-195) is a non-coupled humanized mouse monoclonal antibody directed against the cell-surface myelomonocyte differentiation antigen, CD33, with anti-leukemic activity that reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells.Lintuzumab has antitumor activity and induces cell death directly via CDC or ADCC. Lintuzumab has anti-tumor activity and induces cell death directly via CDC or ADCC.

CAS Number: 166089-32-3

References: Sutherland MK, et al. Anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia. MAbs. 2009 Sep-Oct;1(5):481-90.

• Artikelnummer: TGMT9901A-065-1mg
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T9901A-065-1mg
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK