LRP4 Antibody, Clone N207/27: APC

Mouse Anti-Mouse LRP4 (Extracellular) Monoclonal IgG2A

Target: LRP4

Conjugate: APC

Product Type: Monoclonal

Clone Number: N207/27 (Formerly sold as S207-27)

Immunogen: Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4

Swiss-Prot: Q8VI56

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects the extracellular domain of LRP4 ~215kDa. Degradation product can be seen at ~150kDa.

Cellular Localization: Membrane

Scientific Background: Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.

References: 1. Bennett V., Baines A.J. (2001) Physiol. Rev. 81 (3): 1353–92.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-418D-APC
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-418D-APC
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG2a
• Human Gene ID: 83469
• Wirt: Mouse